The numbers of SARS-CoV-2 / COVID-19 diagnostic tests are exploding. These tests detect either viral RNA or antibodies to virus particles. But, which is best? That, of course, depends on what question is being asked. Read more
Lately I’ve been thinking about immunology, and not just because it is flu season, it is because Digital World Biology (DWB) is collaborating with Shoreline Community College to design a five-week bioinformatics course that will be component of their one year immuno-biotechnology certificate (1).
An aspect of the course will cover the ways in which industry studies and utilizes components of the immune system from vaccines to making antibodies to measuring T-Cell Receptor (TCRs) repertoires as biomarkers. In the classes, bioinformatics methods will be used to to ... Read more
Like many people I know, I suffer from allergies, and sometimes asthma. I take drugs to control the symptoms, but they don't cure the condition. Plus, I know there can be side effects that might not be so pleasant.
This is why I like hearing about sequencing projects that target the VDJ-ome.
I have this fantasy about the things we could do with that information
In a normal immune response (diagrammed below), antibodies on the surface of immature B cells bind to allergens (pollen, dust, whatever). That binding event, plus some help from T cells, stimulates those immature B ... Read more
