Structure Collections

A collection of antifreeze proteins. Antifreeze proteins are found in a variety of species that tolerate cold temperatures.  These include arctic fish, antarctic bacteria, plants, insects, and mold.  

All of these proteins bind to water and lower the freezing point.  Can you figure out what these proteins have in common besides their function?

The Beautiful Brain structure collection accompanies the traveling art exhibit:  The Beautiful Brain:  Drawings of Santiago Ramón y Cajal.

Learn more.

These structures are part of the Bio-ITEST curriculum.  

This collection contains the four major types of biochemicals:  carbohydrates, fatty acids, nucleic acids, and proteins.  Worksheets and eight unlabeled structures give students a chance to practice identifying these four groups of macromolecules.Two worksheets can accompany this investigation:  
     - DNA structure and identifying nucleotides 
     - Investigating biochemicals.

Chemical and molecular structures that accompany the upcoming edition of Biotechnology:  Science for the New Millennium, by Ellyn Daugherty.

Chemical and molecular structures that accompany the Bio-ITEST Genetic Testing curriculum strand.  Includes NEW structures!

Structures of immune cascade complexes from bacteria. These include CRISPR complexes from different bacteria,with guide RNA, target DNA, and the Cas1, Cas2, Cas3, and Cas9 nucleases. This collection of structures can be used to show how bacteria recognize and destroy viral DNA. This system has become an important tool for genome engineering.

Investigate structures of DNA and determine if other molecules (protein or other chemicals) are bound in the major groove of the DNA or the minor groove.  Use this collection of structures to see how molecules interact with DNA.  Both proteins and drugs bind to specific sequences in DNA by recognizing the three dimensional shapes.

A collection of structures for exploring DNA, different forms of DNA, and deoxyribonucleotides.  Learn more about the different forms of DNA structures in our blog post, The A, B, Z's of DNA.

These structures show human proteins where missense mutations are associated with disease. You can view these structures, by downloading the collection and open it in the Molecule World iPad app.

These structures are from different forms of hemoglobin.  You can use these to compare hemoglobin with and without oxygen and the hemoglobin structures found in two types of sickle cell anemia (Hemoglobin S, and Hemoglobin C).

This set of immunology-related structures was created with an innovation grant from Shoreline Community College.

These structures are from aligned pairs of drug-sensitive and drug-resistant influenza proteins bound to different types of antiviral drugs. Comparing the pairs of structures shows how a single base mutation can allow a virus to become resistant to a drug. 

A number of victims were found in compromising circumstances.  How did this happen?  Can you solve the mysteries?

Structures used in the Project Violet Exploration at Fred Hutch.

Molecular structures of selected receptors and some of the chemicals they bind like capsaicin and wasabi.

These structures can be used to show the affect of a frameshift mutation and to examine temperature sensitive mutations.

Read more about the biochemistry of melanin production.

Sugar (Glucose and sucrose) and the building blocks of sugar:  water, hydrogen, and carbon dioxide