We have been using molecular and chemical structures for many years to improve our understanding of biology. As we started using molecular models more frequently, we realized it would be helpful to have defined sets of structures that could help students meet specific learning goals and use guided inquiry to investigate phenomena.
Structure collections help us in the following ways:
- Structure collections save time in preparing for class. Instead of downloading twenty structures for twenty student devices, we can download one collection on each device or have the students do this.
- Once a structure collection has been downloaded, students can work with molecular or chemical models without needing to access the internet.
- Collections save time in searching databases.
- We avoid the problem of whether to download the asymmetric unit or the biological unit.
- We avoid problems where similar characters are frequently mixed up, like 1' and l's or O's and 0's.
- We don't have to hunt around and download multiple structures when it's time to grade assignments.
- We can store annotated structures on our mobile device.
- We can organize structures in pairs to make it easier to compare structures with and without mutations.
Each of the Molecule World structure collections has been compiled with certain learning goals in mind. We have added collections over the years to accompany museum exhibits, textbooks, and curriculum. If you have an idea for a collection, let us know! We're happy to help.
|Beautiful Brain Collection||
The Beautiful Brain structure collection accompanies the traveling art exhibit: The Beautiful Brain: Drawings of Santiago Ramón y Cajal.
These structures are part of the Bio-ITEST curriculum.
A collection of biochemicals: starch, sugars, lipids, fatty acids, amino acids, DNA, tRNA, and protein.
Chemical and molecular structures that accompany the upcoming edition of Biotechnology: Science for the New Millennium, by Ellyn Daugherty.
Chemical and molecular structures that accompany the Bio-ITEST Genetic Testing curriculum strand. Includes NEW structures!
Structures of immune cascade complexes from bacteria. These include CRISPR complexes from different bacteria,with guide RNA, target DNA, and the Cas1, Cas2, Cas3, and Cas9 nucleases. This collection of structures can be used to show how bacteria recognize and destroy viral DNA. This system has become an important tool for genome engineering.
|DNA Binding Lab Collection||
Investigate structures of DNA and determine if other molecules (protein or other chemicals) are bound in the major groove of the DNA or the minor groove. Use this collection of structures to see how molecules interact with DNA. Both proteins and drugs bind to specific sequences in DNA by recognizing the three dimensional shapes.
|DNA Exploration Collection||
A collection of structures for exploring DNA, different forms of DNA, and deoxyribonucleotides. Learn more about the different forms of DNA structures in our blog post, The A, B, Z's of DNA.
These structures are from different forms of hemoglobin. You can use these to compare hemoglobin with and without oxygen and the hemoglobin structures found in two types of sickle cell anemia (Hemoglobin S, and Hemoglobin C).
|Immunology Basics Collection||
This set of immunology-related structures was created with an innovation grant from Shoreline Community College.
These structures are from aligned pairs of drug-sensitive and drug-resistant influenza proteins bound to different types of antiviral drugs. Comparing the pairs of structures shows how a single base mutation can allow a virus to become resistant to a drug.
|Molecular Murder Mystery Collection||
A number of victims were found in compromising circumstances. How did this happen? Can you solve the mysteries?
|Project Violet Collection||
Structures used in the Project Violet Exploration at Fred Hutch.
|Receptors - hot stuff Collection||
Molecular structures of selected receptors and some of the chemicals they bind like capsaicin and wasabi.
|Siamese cats Collection||
These structures can be used to show the affect of a frameshift mutation and to examine temperature sensitive mutations.
Sugar (Glucose and sucrose) and the building blocks of sugar: water, hydrogen, and carbon dioxide